His Grace Emmanuel Cardinal K. Nsubuga (later Cardinal) was consecrated on 30^th October 1966 to become the first Ordinary of the newly created Archdiocese of Kampala.

Emmanuel Kiwanuka Nsubuga was born on 5 November 1914 to Felix Nsubuga and Estella Nsubuga at Kisuule village in Mityana in the then- Kampala Archdiocese (now in Kiyinda-Mityana Diocese). In August 14^th 1930, Nsubuga left Bukuumi accompanied by senior seminarian Joseph Mukiibi to start his journey of priesthood; they passed his home at Kisuule – Mityana for the blessing from his parents. The prelate was ordained a priest in 1946, with his long-time friend Fr. Joseph Kyeyune.

At 51 years of age, Nsubuga was appointed as the First Archbishop of the Metropolitan See of Kampala, receiving his Episcopal Consecration at the Nakivubo Stadium of Kampala on October 30, 1966, from Cardinal Laurean Rugambwa assisted by Archbishop Guido Del Mestri and Bishop Jean – Marie Ogez. Archbishop Nsubuga was elevated to the Cardinalate at the age of 61 on May 24, 1976 by Pope Paul VI, with the title of S. Maria Nuova, becoming thus the first Cardinal from Uganda. Retiring from the Pastoral government of his See at 75 years of age on February 8, 1990, he was succeeded by the future Cardinal, Archbishop Emmanuel Wamala.